Penile curvature, often associated with Peyronie’s disease, is primarily caused by the development of fibrous scar tissue (plaque) within the penis. The exact cause of Peyronie’s disease is not fully understood, but several factors may contribute to its development:
- Trauma or Injury: Some cases of Peyronie’s disease occur following trauma or injury to the penis, such as during sexual intercourse or other activities.
- Genetic Predisposition: There may be a genetic component that increases the risk of developing Peyronie’s disease.
- Inflammation: Inflammation within the penis can lead to the formation of scar tissue. Chronic inflammation or repeated episodes of inflammation may contribute to the development of Peyronie’s disease.
- Microvascular Issues: Problems with blood vessels in the penis may interfere with normal healing and lead to the formation of scar tissue.
- Tissue Plaque Formation: The development of plaque or fibrous tissue within the penis is the hallmark of Peyronie’s disease. This plaque can cause uneven tension during an erection, leading to a curvature or bending of the penis.
- Connective Tissue Disorders: Some individuals with connective tissue disorders may be at a higher risk of developing Peyronie’s disease.